DPCstruct | MC54080

Metacluster Properties and Pfam Annotations

Number of structural domains619
Mean domain length (aa)286 ± 66 aa
Standard deviation of domain lengths66.39
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score81.57
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)15.01
Pfam Score65.44
Assigned Pfam label(s) CL0125- CL0464- CL0176- CL0159- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M3TM97 2-208 RKTRCSKTLFFITRGRESFRYQLCDHYKQKRHQFDEDFRSLLKALKIALVEKYPLKKGAKIQGEHCFEYEADDIISFYKKKDPNNYV…
A0A4Y2S1D8 116-392 SINVVDGGFLLHRVQWNVGCKFSSICDQYVSYLIKRYGEKCIVIFDGYGDANNTKLAEQRRRSITKMSVDINFEETVTVTVQQEHFL…
S4MLR8 1-204 None
A0A3C1VIC7 7-252 None
A0A7R9KTA9 1-158 None
A0A3R8QWE5 13-234 None
A0A6S7GJE9 41-431 None
A0A6S7GL81 37-216 None
A0A6S7GN85 7-229 None
A0A2H0NCQ8 24-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.