DPCstruct | MC54004

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)155 ± 16 aa
Standard deviation of domain lengths15.63
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score77.99
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)23.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G8Q6D0 193-339 VDRSRRKVREVFRPKRDTAAGAPITRDFEFVPPDQQTGGHVRAYYREVIGRGRLRGVFSQDRLDKVLALPWKNWEKGKAGLYGYILL…
A0A485AV92 3-153 ECFDEIEILDTEKEPLITTKFKKVLWTVLPKGKYPWDEISKIIASNTQKTSASDSDREVIESRLKLINVYKPDFIATGHAGFNGYFI…
A0A099S6J4 748-865 None
A0A0Q8EMN2 59-228 None
M8E034 138-304 None
A0A4Q2HRL7 3-151 None
A0A0C1Y2L7 279-439 None
A0A7V9HXJ7 327-474 None
A0A1C5T641 305-467 None
A0A3E0PD84 340-492 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.