DPCstruct | MC53915

Metacluster Properties and Pfam Annotations

Number of structural domains248
Mean domain length (aa)287 ± 71 aa
Standard deviation of domain lengths70.50
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score72.35
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.59
Pfam Score97.02
Assigned Pfam label(s) PF01184- PF05890- CL0257- CL0184- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A123VRN5 2-175 TWVTNQSVVLQALLGGLFTWFCTIMGSAVVFFFKTVSRRLLDTMLGFAAGVMIAASFWSLLAPSIEYAESSYGNLAWIPAAVGFAAG…
A0A4Z2BNB3 97-399 LTITRRRAIGSTLLISAAPFLILFLIPVQSNSDQHQNLLKILLSFASGGLLGDAFLHLIPHALAPHSHHGDDHGHAHKSEESHGHSH…
A0A146HJZ8 2-332 None
A0A7S4SAW9 92-345 None
A0A343TGZ3 3-166 None
A0A287XHI9 2-248 None
A0A1S3Q7N6 3-228 None
A0A2K5NDM6 137-466 None
A0A446JR54 46-232 None
A0A7E4W563 2-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.