DPCstruct | MC5379

Metacluster Properties and Pfam Annotations

Number of structural domains1197
Mean domain length (aa)149 ± 24 aa
Standard deviation of domain lengths24.36
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.50
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)15.90
Pfam Score86.92
Assigned Pfam label(s) CL0023- CL0123- PF06918- CL0306- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8YCQ6 372-528 MEEAILEGLRALGLADYLGGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMQVTATLGARAVKVFEEAKPNSELCCKPLC…
A0A1E3HGK4 19-173 RAGRVLRHQLDGVAYSDDTPQQEEDSLLITINFSIDYSNPSKSLQGQHKSVGVIMGQVAELPNVYHTKFHYNLMLGMTPAPSEPPSH…
A0A2N0QS73 99-239 None
A0A2N0QRI0 54-195 None
A0A2N0PXR7 141-285 None
A0A819Q8V2 421-570 None
A0A819MRY8 233-361 None
A0A6D2JMA4 30-172 None
A0A2B4S452 38-199 None
A0A835CS87 9-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.