DPCstruct | MC5378

Metacluster Properties and Pfam Annotations

Number of structural domains186
Mean domain length (aa)188 ± 37 aa
Standard deviation of domain lengths36.88
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score75.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)20.49
Pfam Score98.28
Assigned Pfam label(s) PF04366- CL0062- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y8P6Z7 12-209 None
A0A4S4KRX2 8-156 None
A0A371DQJ3 10-219 None
A0A7S3GNH5 130-342 None
A0A1M6M269 98-241 None
A0A5C9AXV6 23-185 None
A0A485L2N1 598-807 None
A0A2P6VQ25 906-1122 None
C5FW33 52-277 None
E4RXN9 223-376 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.