DPCstruct | MC53772

Metacluster Properties and Pfam Annotations

Number of structural domains345
Mean domain length (aa)130 ± 27 aa
Standard deviation of domain lengths26.57
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.87
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.85
Pfam Score96.23
Assigned Pfam label(s) PF21691- CL0016- CL0219- PF01657

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P5WX69 14-131 TTKAQQPAYRHHECPNTTTTSYQANRNTLLSSLSSNSIHANHGFFNTTVGTSRKTVYGLFLCRGDYFITFCRSCVALAADDIARCCP…
A0A2I0BB74 18-128 LPAPDTGFVEALCNVASFTAGDPFTESLSYVLADLVTVASARAGHDYYNISPYPNAFAYGHASCSGNLTAGDCADCLHAAVRAVSSA…
M4DB06 87-199 None
A0A6V7PZV4 341-457 None
A0A0D3DL22 87-204 None
A0A3P6C0E2 6-94 None
A0A396H4Q9 97-243 None
A0A2G2WTB5 13-109 None
A0A2G2WMX4 27-141 None
A0A3Q0FGE1 16-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.