DPCstruct | MC5369

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)101 ± 8 aa
Standard deviation of domain lengths7.97
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score69.56
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)47.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4D6L5D9 1-100 MMHISAERSDEMGNKKVVTRVVYPFAMVKPGGREGDVTLNDINERILMPPTRPVRHPVGDFACRPCVSAEGPGLSGKAVVALTRIHT…
A0A445KNH5 138-235 TVAPTENDDMRNKKVVTRVVYPFAMVKPGGREGDVTLNDINERILMPPTRPVRHPVGDFACRPCVSAEGPGLSGKAVVALTRIHTQG…
A0A816MNX0 279-386 None
A0A444C9E4 2-116 None
A0A5D3BG61 93-201 None
A0A4S4D9R9 161-266 None
A9T1Q8 376-490 None
A0A453KYD2 268-366 None
A0A1E5VNA2 219-318 None
A0A835KHR9 272-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.