DPCstruct | MC53682

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)193 ± 20 aa
Standard deviation of domain lengths20.15
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.39
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)37.68
Pfam Score100.00
Assigned Pfam label(s) CL0193

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A259D372 1-128 MAATKSLGEKIKVTAGLGWGRFGSYESIGSPFGDRPEAGTVGRPNVDQWFKGDAAVFGGVEVKVTDTLTVKGEYSSDAYTLEDDERG…
A0A377DZ99 58-256 DKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGYLGTSGNVKNPLCSASDKYCYRDNSYKQAGS…
A0A376YIC8 20-222 None
A0A432ZKC4 424-610 None
A0A447PX65 350-552 None
A0A6N3UB84 107-306 None
A0A5A7N6A2 124-330 None
A0A259N7E0 1-193 None
A0A1I6GQZ4 96-276 None
A0A522EX48 339-540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.