DPCstruct | MC53669

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)175 ± 7 aa
Standard deviation of domain lengths6.87
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score80.19
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K6V586 756-928 TPGAYLLKGDHHSITLNIKQKKSGSHTYSLYDPQVGNVDLTPTSSEGGDALYHLLDHYLQGKDKDGRTRAQQYGFEKMGNKYAFNAY…
A0A377VV28 301-482 SLSIFFNNDVNNLLITTPAHTLIIQHFDSLYRVTDPNFGHAEFPSLSDAVHFLEAGIQLTPVLSKYYGLSGSNVRSHLFVYDISNIS…
A0A2U8I5X5 31-207 None
A0A2U8I387 288-450 None
E0WQT5 1-183 None
C4K3P9 653-820 None
A0A376U7Y4 238-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.