DPCstruct | MC53488

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)173 ± 23 aa
Standard deviation of domain lengths22.79
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score75.82
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)34.19
Pfam Score98.44
Assigned Pfam label(s) CL0028- PF03169

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M4EJI8 28-191 ITSVGNICNTNLLPLGSPWTCPGYEVFYNASIIWGVIGPRRMFTKEHIYPGMNWFFLVGILAPVPFWYLSKKFPEKKWLKHIHIPLI…
A0A1D6L4S1 390-578 MYTAQLVGTVVAGVVNLAVAWWMLDNIENICDVEALHPDSPWTCPKYRVTFDASVIWGLIGPGRLFGQHGLYRNLVWLFLVGAVLPV…
R1G156 364-510 None
A0A4S4DPC3 341-519 None
A0A4S4CWP1 529-731 None
A0A820LPG9 1-128 None
A0A2S5B7K2 229-399 None
R8BVJ1 419-605 None
A0A814TX37 165-340 None
A0A4S9T5E0 3-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.