DPCstruct | MC53388

Metacluster Properties and Pfam Annotations

Number of structural domains1894
Mean domain length (aa)307 ± 79 aa
Standard deviation of domain lengths79.08
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.77
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.78
Pfam Score93.09
Assigned Pfam label(s) PF00384- CL0608- CL0015- CL0177- CL0051

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A836D836 432-801 LIIIGGGSGGLAAAKEAAKYDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALRDSRNYGWNVEETVKHDWERM…
A0A6P8IKJ7 76-417 QLTLSLNNWLELPGLEFQDWLREHRHEAVRKPCTLVKNRIESPGNSYDRATTSHIAEYYKDYVDKMDLSGYFSNDSKVLSVKHGSDG…
A0A812NMD9 451-846 None
A0A421JW65 45-488 None
A0A445CWX7 2-212 None
A0A2K3JFL5 194-483 None
W6Y300 6-363 None
A0A146HY12 201-711 None
A0A146I571 735-1093 None
A0A1I3NBW8 20-343 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.