DPCstruct | MC53226

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)367 ± 91 aa
Standard deviation of domain lengths91.46
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score87.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)39.02
Pfam Score86.05
Assigned Pfam label(s) PF21680- CL0003- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S6DJH4 19-328 GFDIVRFKTGTPPRVNSDSIDYSKTEIQPGDDLPRAFSYETTEFIMDQLPCWLTYTNGETHQVIDDNLHLSAMYSGMIKGTGPRYCP…
A0A7J6AR81 516-994 LDRGRYREFVQSQLLKMPRLTVIEGSVEDLIVLKEVLGLKLGRMRTGTPPRIIKDTIDFSLAKLHLPDPQPTPFSFVNRHTHCKPED…
A0A2S4WLA2 79-550 None
A0A379B1M6 51-369 None
A0A090VXD3 53-368 None
A0A0G2DSZ5 148-580 None
A0A6J8E032 39-356 None
A0A1I7Z6S4 1-310 None
A0A7S1NPD8 373-843 None
A0A077ZHG4 689-1159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.