DPCstruct | MC5312

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)198 ± 32 aa
Standard deviation of domain lengths31.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.55
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)25.95
Pfam Score100.00
Assigned Pfam label(s) CL0376

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2K5Q3 3-170 QDTLSIICISYFTAFLGEGLTWLFVYRTEKYQKLKAEVDKQSKRLERQRDASELSIDRTAKKRLEKQEERLKNINRELSMVKMKSVF…
A0A1B0D1D1 15-236 FLPIVVITFLVGIIRHYVSMLISSQKKVELTQIQDSQAMIRARLLRENGKYLTSQAFAMRRHYFNNEETGYFKTQKRPPVSPNSTAM…
A0A2D4PV25 1-127 None
A0A6A4K3S1 485-714 None
A0A0L8VMC0 299-536 None
A0A6P8VDS2 4-164 None
A0A7R9A6D2 1-179 None
A0A090L5H1 62-288 None
A0A177BC01 115-315 None
A0A1V8SYR0 2-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.