DPCstruct | MC53047

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)573 ± 96 aa
Standard deviation of domain lengths95.91
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.12
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.39
Pfam Score78.07
Assigned Pfam label(s) PF12660- PF19336- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K3FFK2 22-521 LLVALHKSGGISFWDVTIPLVDERSIRLCAVDRTYAVPFDPPHHLARPNFIKVIDIDCENIILVVGFTNSRVVCVTYHAYAKIVNKL…
A0A137Q4S7 513-1154 VTPYLIETFQTTSAELSHTKQTLHAQIVSICWTPHPDFGVTPVPECNGSLLISGSRAGGILLLRQVFLINTDVISRQLSLRYVDKSL…
A0A0M8MTU0 316-858 None
F4PXX8 115-671 None
K2S8J2 317-939 None
A0A177WP49 75-670 None
A0A2P2MFC5 16-605 None
A0A1V8SKY6 100-707 None
A0A6J0YYK1 177-812 None
A0A5N5QLJ9 20-624 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.