DPCstruct | MC53030

Metacluster Properties and Pfam Annotations

Number of structural domains166
Mean domain length (aa)257 ± 48 aa
Standard deviation of domain lengths48.39
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.85
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.98
Pfam Score92.56
Assigned Pfam label(s) CL0029- CL0123- PF02946- CL0219- CL0687

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8M8M5 1-207 MFCASCIVESHSRLPLHWIERWNGQFFEASSLRSLGLRVQLGHGPHSRCINPKQAHSDDFAVIHVNGIHSVAVNFCGCPGAEEHYMQ…
A0A0C9VDQ4 172-473 TGPPSFGLYSPGHEFTPHQLNGYMGYDDGDDGVDVVEETDWLGLDGFGTGNDDEDVDLDPRSQTRRKRYQASDAPLHDWLQVRQIFL…
A0A6A4GLA6 160-392 None
A0A7J5YDP7 2-200 None
A0A6A4GNB8 53-310 None
A0A6A4GQX8 1-196 None
A0A6A4GYZ1 16-279 None
A0A6A4H118 14-221 None
E3KK71 37-290 None
E3KPG4 196-479 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.