DPCstruct | MC52991

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)191 ± 32 aa
Standard deviation of domain lengths32.10
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.74
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)25.33
Pfam Score86.32
Assigned Pfam label(s) PF18035- CL0036- PF05529

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W0E2B9 1-193 MEVQTTVIHVVLGINLLMNVILLFPWFDNVKRWFIQFYAYNMVFKTIRHIFNIFYVMIGVLLVDSAYKMNITESKLLEYQSQRNMYL…
A0A4Z0A1Y5 2-198 TFMLLAGEMGTFCLLVAPLPFQVKRKLFHFLSESPVIAKIAYGLKISFIFVAILFVDALQRMFRVTAEVELAKTGQQIQDVRTETNF…
A0A1E4T9C2 327-495 None
A0A654GK30 2-161 None
A0A1W0XA20 74-292 None
F4Q7U5 147-301 None
A0A1B0BRT6 1-219 None
A0A1S8VFS8 21-229 None
A0A183SFM1 795-1055 None
A0A7F8RX41 145-344 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.