DPCstruct | MC52898

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)135 ± 17 aa
Standard deviation of domain lengths17.16
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.52
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3NYA9 85-225 LREQIAALERSGAYPALDRSADIAGPDANGNGVRDDIEAWINSQQLSDAQKKALMQRGRALQKTLLVSLADQAALQVTGEGLMASSK…
A0A0G1YR73 9-136 LPPPPDLAQVDATIEGIDANGNGIRDDVEFAIFEKYPNDIKIRAATLQYAKALQQGLTQVTNSGTWIAASQQEERSLRCILENVSQT…
A0A1W1UN86 18-156 None
A0A7T9C877 116-239 None
A0A1F3SVL4 431-567 None
A0A2S8RMU5 15-148 None
A0A4U1WAN5 6-133 None
A0A0S8CU15 103-229 None
A0A7W2RMB8 103-236 None
A0A0B8P029 125-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.