DPCstruct | MC52854

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)136 ± 19 aa
Standard deviation of domain lengths18.74
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)33.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C2Z4N2 1-123 MDTWKKGFGENLEEVDNALIKVYQNMRDVPHEELQGASENVLTLAKLYDVDLNEATRGAGQVMSQFNLSTQETFDLLAAGAQAGLNY…
A0A6H5REI9 163-312 KFYATTNLSGQALENLKAVAQDVFKTGVTDSIDEATDATSLMKQAFKDLNDTDLAKLTSQVMLLSDRTGTDVAENVTGTTQLMKAFG…
A0A2B3QD49 302-452 None
J8AVZ9 3-102 None
A0A412XZJ6 205-345 None
A0A6H0UJ97 44-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.