DPCstruct | MC52748

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)345 ± 27 aa
Standard deviation of domain lengths27.29
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score78.25
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)28.89
Pfam Score60.00
Assigned Pfam label(s) PF11277- PF08689

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B4DDR8 172-508 TVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKD…
A0A2G9SIY7 1-333 MLSSHSEQLHCTGFPTVHAIVMLEGTMNLTGEARPFVEQLNTVKRMQKIPSHLFLLEVWKACIVGLIESPAGTDELKWTAFTFLKIP…
U9TNW8 1-373 None
A0A2P4Q6G1 1-373 None
A0A2J7RQD3 231-569 None
A0A6G0YZ34 451-741 None
A0A397V815 1-367 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.