DPCstruct | MC52746

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)537 ± 107 aa
Standard deviation of domain lengths106.51
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.43
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.28
Pfam Score80.42
Assigned Pfam label(s) PF21385- CL0105- PF08326

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G9SEX8 1-580 MQVARQSLTTYVIIMNNSHIEIDVHRLSDGGLLLSYDGNSYTTYMKEEVDRYRVTIGNKTCVFEKEKDPTVLRSPSTGKLLQYTVED…
A0A453AGY6 18-463 RRHISLVHSTVSLNIEESKYTIETIRSGQGSYRLRMNGSVIEANVQTLCDGGLLMQLDGNSHVIYAEEEAGGTRLLIDGKTCLLQND…
A0A6N2LWH0 247-932 None
A0A6I9XS55 445-946 None
Q13085 685-1362 None
K0ETW2 503-1052 None
A0A7E4S774 315-900 None
A0A183H5Z4 401-814 None
A0A6I9XCZ9 193-590 None
A0A1I8IGY0 218-638 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.