DPCstruct | MC527

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)253 ± 27 aa
Standard deviation of domain lengths27.25
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.65
Mean fraction of residues predicted as intrinsically disordered0.84
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)23.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E0HHJ2 41-320 VIHVKAGETRELAPADGVLSLQRLVLEDNAVLSLAPGLGQVQIDVARAEIGRNVKIVARGEAGADGQPGASIPGQAPTCSAGKPGTA…
A0A368DQY2 122-331 QGPLNLLYNGTDGINGKNQRNRGTPLLLRDGKDGEHGPDGTNGASANNYTAHLWRDSSFIYVHITEDISNHVYRYQMTSGNNIHFDL…
A0A848E831 254-492 None
A0A014PES1 3-261 None
A0A843YTW2 45-270 None
A0A7Z1K0Y7 1-263 None
A0A2X2JL56 146-370 None
A0A7G5MNZ3 338-645 None
A0A3E1NUT8 1-230 None
H8MWX5 449-720 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.