DPCstruct | MC52595

Metacluster Properties and Pfam Annotations

Number of structural domains26312
Mean domain length (aa)122 ± 21 aa
Standard deviation of domain lengths21.19
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.05
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)10.85
Pfam Score54.45
Assigned Pfam label(s) PF11797- CL0003- PF01324- PF20254- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662RZM0 3-109 RPAVAFMNVIISGEVRLGQSFEIKGEVRNRGEVKVTNVEIMVYLEGKVLKKVSLGEISPSEREEFTIEVTIPSDIALGPHNLILLLT…
A0A6F8Z1C3 165-267 ANHNPRASVREGLDLKRKPGKQVTLRGRGSDPDGDRLTYRWWQYTDADTYPGTVTLNDANTPTVSFTVPADAVPGQTIHLILEVTDD…
A0A6M1LEH1 581-718 None
A0A1Y4HFA8 178-297 None
A0A6P4EMU5 204-320 None
A0A099NZS1 673-780 None
A0A6P4EDR3 85-212 None
A0A1G1A4F1 783-925 None
A0A7V3AFN6 413-524 None
A0A7V3AFB3 591-685 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.