DPCstruct | MC525

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)106 ± 2 aa
Standard deviation of domain lengths2.41
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score84.78
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)46.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A124SAJ5 63-164 RDLKYNRRSQSVQLRKLDHSVAQAMRVASSPQEWRERGKKLYSENNFVMATMCFERAGDRMWEKLAKALGLRTFAEQMRGMNFEAAS…
A0A453CVH2 80-185 MFDYWKKLCLVEVRLLDSSLIQAMQTGSSSDDWRLRGTKLFNEGQFEMATMCFEKAGDAHREKLARAAGLVATANRVISTNLELGKA…
A0A843W018 792-896 None
A0A7J6W4L6 56-162 None
A0A7J6W032 78-182 None
A0A4Y7INR1 570-673 None
A0A6S7FTA4 88-197 None
A0A1R3HQH9 277-380 None
A0A0P0WE98 1411-1519 None
A0A287RVF2 483-587 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.