DPCstruct | MC52481

Metacluster Properties and Pfam Annotations

Number of structural domains2200
Mean domain length (aa)167 ± 31 aa
Standard deviation of domain lengths30.69
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)12.31
Pfam Score89.07
Assigned Pfam label(s) CL0023- CL0270- PF19319- CL0479- PF08350

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G4RP59 23-164 CPSAIIVGPSNASLIATYISKAHKAVYIEVYALTWKELADTLAALANRGVQVYLVLSANVYGGIPTTEKKLVQYLQSAGVNIAFNND…
A0A2K1Q562 17-172 EPRVINNAEAHDACLTDILQLAQQRVVIVSPWVSLFRLRESGILSTMQQAVERDISVELYTDYRFNSFTNHRFDEEKNAQFKACCTE…
A0A426TQR1 16-170 None
A0A158R4G8 41-202 None
A0A2H6BNC0 34-202 None
A0A841JRE1 78-260 None
A0A2Z4FMJ3 277-447 None
A0A819S457 228-400 None
A0A212DSE5 1-136 None
G7EFX4 202-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.