DPCstruct | MC5245

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)102 ± 12 aa
Standard deviation of domain lengths11.85
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score83.06
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)20.99
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S3WQ43 9-136 QIAAGDHPQPHPCCSRAFEIASAHLPEEDWADLQTLVEDADTALLHFECFTLPDSDAIGFKLLSTPWTDHHLGQFWGYDLSTLQALQ…
A0A7X5D2U8 18-115 REAGETDGFPEISHVITISTEHIRPETASLLDADAVELIVWKKDKYGYVVMTIGWELYGEDIPEDLRACVQYAAEHNCDWLCLDGDA…
A0A1I7FML3 1-88 None
A0A3A6Q824 61-164 None
A0A1L3T006 77-164 None
A0A318KZ60 59-149 None
A0A2N4UPZ6 5-116 None
Q7NYQ9 7-106 None
A0A370L9S6 50-189 None
A0A7C1QTP7 211-318 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.