DPCstruct | MC52434

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)273 ± 37 aa
Standard deviation of domain lengths36.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score70.42
Mean fraction of residues predicted as intrinsically disordered0.53
Mean length-normalized TM-Score0.27
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)39.79
Pfam Score70.28
Assigned Pfam label(s) PF16543- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P6FZC3 1-269 MPPKQQPKADLAKKQKQVEDKTFGLKNKNKSKNVQKYVQSLKQSVQPKPDASKVAAKKKKEEEKAREQELNELFKVAISQPKVPVGV…
M7PKZ9 1-241 MPQKKTAPSVKKNPQKIVEDKTFGLKNKNKSSKIQAHIRQIESQAANIGKNKITKEKEMQKKEQTEKKIAEESRKMELSELFKQPPQ…
A0A183M3A1 1-233 None
R7UEL9 10-301 None
A0A2I0HL54 1-268 None
A0A162QNH6 6-276 None
S6B750 14-279 None
A0A0K2VDD7 1-209 None
A0A5N5SSY1 7-281 None
A0A7V5I9Q8 29-337 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.