DPCstruct | MC52223

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)385 ± 80 aa
Standard deviation of domain lengths79.71
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score68.85
Mean fraction of residues predicted as intrinsically disordered0.60
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)36.87
Pfam Score94.43
Assigned Pfam label(s) PF04046- PF04037- CL0475

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A803LLD4 8-371 TGVDSAAAATVLEEVEVTYVPEKADLDDDLLDDFKRVFEKFSFKEPEGDEADEKKDEIDQDAAAKKKADSDSDEEDQDNQLKEKGIS…
T0MEE9 1-278 MNSDYSFIYKNKSLNKKERKKVIRQKKYEELKKIVPFPELLDIEDLKCEDIIKYNKLKSMYKGVHVIKRWKHKNIFPLNYKQKEYEI…
Q4UC05 58-534 None
R1BL73 2-375 None
A0A3M7LYC0 391-851 None
A0A2P8Y8K8 254-669 None
A0A232FBW1 35-565 None
R0KXW2 14-248 None
A0A7S4KHB4 10-355 None
A0A0B2UIV7 21-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.