DPCstruct | MC52204

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)228 ± 7 aa
Standard deviation of domain lengths7.18
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score87.55
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)41.37
Pfam Score100.00
Assigned Pfam label(s) CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4Z447 2-228 EKWLKGFLAKLKRTSTRTQKCRLISSVERMKFEEDVHACLWQYVRFGEDEGEIFNKNKISLEKIKLTDYQKVLLKSDDSLKDRFLSR…
E4XST3 37-265 RENGKNEIEKWLEGFLAKLKRTSTRTEKCRLILAVERMQFEDDWYAAWWKHVRFGEENVKILDTGINVGKKDLQKIKITEFQKELLK…
E4YMZ2 1-226 None
E4Y7V2 11-233 None
E4Y743 1-233 None
E4XZJ8 12-246 None
E4XNS7 4-231 None
E4XR09 8-218 None
E4XL99 12-252 None
E4XDQ5 12-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.