DPCstruct | MC5212

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)75 ± 5 aa
Standard deviation of domain lengths4.54
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score87.09
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.16
Pfam Score100.00
Assigned Pfam label(s) CL0616

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7F5R3G3 1-79 MLLKQYPCMWQGLLALKNDQAAVQMYFVSGNEQVAKCSLPKNIDGSTPPLRIFQRMRLEPPQVEGVARKMQVVYSSFFL
A0A5E4D8G2 63-133 ILKKYPIVWQGLPALKNNTAAVQLHFVSGNNVLAHQSLPLSEGGPPLRITQRKWLEASQLEGVARRMTVKT
A0A183E7F5 63-136 None
A0A7R8CJW8 326-408 None
A0A7M5TYE7 710-784 None
A0A183S796 45-119 None
A0A226D9G2 2-68 None
H2XTQ6 78-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.