DPCstruct | MC52077

Metacluster Properties and Pfam Annotations

Number of structural domains535
Mean domain length (aa)175 ± 45 aa
Standard deviation of domain lengths44.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.32
Pfam Score99.29
Assigned Pfam label(s) CL0023- PF01425- CL0269- PF00857

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P2SJH5 24-201 PHGNIGLLIVDFVVGFADPATFGGGNIAPAIARTTRALALARERGWSVAHSRIVYAEDGSDDNVFSLKVPGMATLTEHHPNSAIVPE…
A0A2T3JIG9 3-181 KALVIIDFINDIVDKNGKIPSCAEQVSAHHVIHNANIAIQWARENNVPCIFIKVGFQSSYLELPHQSPMFGKAQQYRALELGHWGTD…
A0A1W1X6X5 4-269 None
A0A7R9A2J4 231-397 None
A0A1X7AJ46 69-226 None
A0A0G4HQD9 157-332 None
A0A6G0XHW0 7-272 None
A0A7R9A3W7 106-284 None
A0A5E8HE15 10-208 None
A0A1Q9CNG1 578-884 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.