DPCstruct | MC51994

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)135 ± 18 aa
Standard deviation of domain lengths18.31
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.06
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)38.06
Pfam Score95.65
Assigned Pfam label(s) CL0020- PF15443- PF01294

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A226NYU1 181-321 SSAIQAAALRRLLEFIDVYWTEAADYLADIEALYEDTGFSERELAGFIASKIYFYLEEYGEAMRFALQCGRWFRIDEPSLYVQRILA…
A0A3Q0JP01 1-85 MIELKEFSLKKLNDIVDDFWPEVSEAIQKIEILHEDKGFPQYKLAALVASKVYFHLGSFSDSLQYALGAGDLFDVRNDTVYVKTI
A0A446J957 5-147 None
A0A2G5UQL4 16-161 None
J9BFR2 76-223 None
B9RWJ0 1-141 None
U7Q0J1 7-123 None
A0A540LZW4 2-138 None
R4XB38 1-153 None
X6MLE9 2-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.