DPCstruct | MC51987

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)420 ± 81 aa
Standard deviation of domain lengths80.62
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.73
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)19.38
Pfam Score67.49
Assigned Pfam label(s) CL0020- CL0004- PF16192- CL0066

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H1W0R0 100-486 RNSPLEIAYGSRATIKNMGYGGGLLHSHVQTYPEGSTQQQVTCYHHKDANNDWFFYPNRHDEDYDPEAEPRFIADGSTIRLIHAQTG…
A0A821B8V7 18-528 HEATNEGDIVRLFHAEQEKFLTCDNYRKKSVVFLRATGRASATSATSSNALWEIEVVQQDPCRGGIGHWSSLFRFKHLATGQYLAAE…
A0A5J4P0A9 203-646 None
A0A1X7SWY4 52-400 None
A0A183SPW0 97-612 None
T1FAS8 15-398 None
A0A6V7X246 171-600 None
A0A5K1K408 3-421 None
A0A034VAR5 28-600 None
B7XKD6 18-341 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.