DPCstruct | MC51984

Metacluster Properties and Pfam Annotations

Number of structural domains367
Mean domain length (aa)177 ± 35 aa
Standard deviation of domain lengths35.46
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.38
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)23.77
Pfam Score43.96
Assigned Pfam label(s) CL0023- CL0021- PF14214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X7T9I3 4-137 VTVQYVNVYLPHKRSRKIKNYSYLSKMDRSSKDIFNPSIIEDFYPTRPNNMEDVSLYEFVANYKFDKIGENGEREYKLRSKPVLPNH…
A0A821AS99 17-193 IKAHLDARYVSAPEAAWRLFEYPLHDKSHAIIRLAVHLPNQQPVYFAEGNEQQALEKAASKDTTLIAWFKLNSKDPDARQYLYHDIP…
A0A834T6D7 41-248 None
A0A834T4M4 352-543 None
A0A1R3KN73 2-128 None
A0A445CC36 1-211 None
A0A1U7XXA1 2-165 None
A0A820USH9 467-688 None
A0A817M6T9 572-784 None
A0A1R3KVY0 608-826 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.