DPCstruct | MC519

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)175 ± 46 aa
Standard deviation of domain lengths45.69
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score78.72
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)35.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A251SNY9 15-139 RDYLKFAAEEFGKDHREIYKWLPTADLKKVAQFGCPSLGRKNVFSAKTMRFCFGIREETVCNKCVLKESCKFANQSVWKKGAKNMDL…
A0A835CDA7 42-215 QKEPMVLKELSPYMTIVVHHLYKEGYFNFANFAKGERFDLSWFDTEYARKYILFAVQKFGKDKQEISKWLSGSDLKQVAMFGCPSFN…
A0A835IKB5 39-210 None
A0A067KT00 13-168 None
A0A1D6GJL9 44-311 None
A0A843WP37 82-313 None
W1NK45 23-154 None
A0A1U8EFU3 322-503 None
A0A835P948 56-243 None
A0A540KS28 302-492 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.