DPCstruct | MC51836

Metacluster Properties and Pfam Annotations

Number of structural domains2421
Mean domain length (aa)117 ± 22 aa
Standard deviation of domain lengths22.26
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score75.79
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.76
Pfam Score95.73
Assigned Pfam label(s) PF02377- PF16599- CL0020- CL0466- PF10152

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5A8C6G2 235-357 None
J9EZG0 99-191 None
A0A7I8VC08 480-625 None
A0A4W6C2N1 163-267 None
A0A0M0K0H8 257-399 None
A0A3Q3ARW4 28-133 None
H3BVJ1 41-153 None
H3BWE2 40-138 None
H3C440 53-158 None
H3CAI4 54-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.