DPCstruct | MC51675

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)192 ± 46 aa
Standard deviation of domain lengths45.94
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score75.06
Mean fraction of residues predicted as intrinsically disordered0.52
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)40.17
Pfam Score98.21
Assigned Pfam label(s) PF06246- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O74370 13-214 TEKRPKDIKSIKSVPICEKHRASVVKDISRKISRIQSATLPEYQIRDLNDAINRLMREKHEWEVQIRDLGGINYLYNKAKLFEDEGE…
E2L9R1 2-152 ASACKSLRECERWRGEILREISRKVSKIQDAGLTDYEVRDLNDEINKLVREKRHWENQIVALGGANYRRNVAMLDDDGKEVPGTKGY…
A0A2G3B6P0 2-139 None
A0A7N4NPS5 5-138 None
A0A4V6A4A9 1-241 None
A0A6A5DPR1 2-241 None
H2B0A9 1-212 None
A0A7S3N955 2-120 None
A0A803JIR3 9-138 None
A0A177WJM4 754-980 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.