DPCstruct | MC51665

Metacluster Properties and Pfam Annotations

Number of structural domains106
Mean domain length (aa)301 ± 72 aa
Standard deviation of domain lengths72.20
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score83.89
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.71
Pfam Score97.35
Assigned Pfam label(s) CL0707- PF03595- CL0129- PF21057- CL0399

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0QJ44 31-355 GTGIIAVGAASLPVDLPGRDSIARAFWVLATAALLLLSVAFAAHWVRHREQALGYARNPAMAPFYGALPMAVLTVGAGTAAVGTEIF…
A0A1H2QSH1 17-279 ILIFVLLCIMYTIKLVKYPKVVLSEFSNPIAGNFFGAVTVAILLLSAFISSYSQILGQSLWIIGTCLTLLLSYFLVSRLFKAKQDLL…
A0A0D3BVM0 478-643 None
A0A1R7T388 207-501 None
A0A5C3MHM7 17-271 None
A0A523CTY2 322-704 None
A0A3P6CKK8 316-486 None
A0A146FIP5 2-213 None
A0A146HAM2 25-365 None
A0A3N4KQ71 1-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.