DPCstruct | MC51609

Metacluster Properties and Pfam Annotations

Number of structural domains225
Mean domain length (aa)118 ± 18 aa
Standard deviation of domain lengths18.35
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.27
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)24.06
Pfam Score79.70
Assigned Pfam label(s) CL0193- PF05662- PF05658

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V7YDA8 15-145 EGKERSVRHVAKGTADTDAVNVRQLNDVLTQSNEYTDLAVEGLNKRLDGMDKRFNRMAAMSSAQSAMAMNTAGLNTYNRLGAGVGHS…
A0A7T2WVM2 13-122 TLTNVSAGVAPTDAVNVQQLNDSLGSVRNQIEHDHRDANGGTASAVAIASLPQAPSPGTSVVAIGGGSHAGQSAMAVGLSTYAGRWI…
A0A1Q7B3Q6 292-435 None
S7J1B1 730-852 None
A0A829W1S3 181-304 None
A0A1Y6FEP4 592-732 None
A0A1C5TD27 333-441 None
A0A809RSD5 17-136 None
A0A1V2VTP6 3-69 None
A0A7T1GXA3 134-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.