DPCstruct | MC51592

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)261 ± 46 aa
Standard deviation of domain lengths45.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.74
Mean fraction of residues predicted as intrinsically disordered0.68
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)20.64
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A166FLJ3 351-637 EAIQQRIAEEQEAKRVRAEAARVAEAARLAEKARLAEQARLAKLEQDRIAEEKARQERAEKAARHAAAERDAAVKRKAAKEQAQRLA…
J4G187 22-250 ETLRWVHQQQGQGPSRLQTETFQRNGIDSPSHPVEFIEVFTVELGDLRLTQETWRAAERWQREAERVVAEEMRRLRAARLATERCKL…
A0A3M7HN66 118-399 None
A0A0C3BEJ5 2-205 None
A0A146I2X7 138-440 None
A0A146I2R5 253-624 None
A0A7S0Y8Q0 270-492 None
K8ELK8 198-430 None
A0A2H3ER71 24-383 None
S7Q0R3 7-261 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.