DPCstruct | MC51411

Metacluster Properties and Pfam Annotations

Number of structural domains2151
Mean domain length (aa)285 ± 73 aa
Standard deviation of domain lengths73.43
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score84.79
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.38
Mean intra-cluster sequence similarity (%)13.17
Pfam Score95.76
Assigned Pfam label(s) PF05380- CL0062- CL0103- PF01155- PF05035

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378ARN8 2-244 LAEITQHWRDGATPVVMAGMVGSNVGWKIAPYLPLPAAFSDIGQQLTAVGDNIWIIPGLCVSRDDNHNVMRGEETQLLGARALAPSS…
B7FYB4 59-325 GVPETSRPISPQQVGSYVVSHLMRITETFLGHDNIKSAVICVPAKFNAAQKLATYQAFRQAGVTVARVVEEPTAAALAYGLNRKEGV…
F4PL12 6-297 None
A0A378A598 3-272 None
A0A2G8LR99 39-334 None
A0A378C3S4 2-238 None
F4PJ17 24-297 None
F4Q5T8 15-270 None
L5JRE6 23-264 None
A0A7C2LFG9 4-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.