DPCstruct | MC5137

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)135 ± 30 aa
Standard deviation of domain lengths29.59
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.13
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)37.73
Pfam Score98.00
Assigned Pfam label(s) CL0172- CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V1EFD0 4-135 FFTRMNSYDIYESLESIHVFALAHVLKRPIVIVSDTVLRDISGEALSPIMFGGIYLPLECSPSECHRSPLVLCFDTAHFSALVAMQK…
A0A7S1A993 362-459 LDSVHVLAVAHALCRPLVVVAPAMQTDHFGVPLTPLFFRGIYLPFECPPELCCQQPLILCFKDAHFMPVVPVRGAATQVRVPLADGT…
A0A4W3H451 152-272 None
A0A812DGL3 77-214 None
A0A183HMZ4 3-178 None
A0A5E4PXZ1 1-106 None
A0A368F850 166-295 None
C3ZYU6 22-146 None
A0A2G8L400 298-418 None
A0A821F3P3 341-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.