DPCstruct | MC50909

Metacluster Properties and Pfam Annotations

Number of structural domains262
Mean domain length (aa)166 ± 26 aa
Standard deviation of domain lengths25.89
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.33
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)17.51
Pfam Score97.34
Assigned Pfam label(s) CL0023- PF04043- PF03140- CL0268- PF04045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445EPA2 16-188 LFVSSFSATAQDLLRSSCSHARYPALCIKTLSPYATGSATPMDLAQAAVRVSLARSRSLSTYVTTLQSQMQQQAPPSTDRAALKDCV…
M1BJQ8 4-102 AHDLVNTLFKQATDPKLKTRYSSCLENYNDGIDDLRGLPALLKSRDYSGLNIHASAALDDPSTCDDNFSDPPAEAPQLKVASEKVQG…
A0A7N0UCQ1 10-160 None
A0A7N0U7Y6 20-195 None
A0A445D9Q5 9-142 None
A0A803PW50 16-191 None
A0A0D9VGQ5 182-406 None
A0A5E4F167 22-179 None
A0A164W0G6 18-224 None
I1I0W3 14-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.