DPCstruct | MC50908

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)174 ± 8 aa
Standard deviation of domain lengths8.37
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score80.50
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)46.01
Pfam Score91.67
Assigned Pfam label(s) CL0673- PF13966

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445EM86 1-179 MLDWKKLRDIRELRWELALRVLVLTPSQVGSSSLVEDIHTNINYDAGEIVTPTPGVKRIFSSPCCLPHIAQAILSGEPSIVEAAAAL…
A0A2R7VQB7 21-196 MANWTAIQNIPQLKWSLLARGTSLMNDSELAILILNMLITMIEYYPSKNEEGAIIWPICKIRLVLSGSQCLPHIVQLLLTFDPTIVE…
A0A182EI93 743-919 None
A0A3Q0JLE1 528-698 None
A1Z7S0 1014-1190 None
A0A445EMA4 103-282 None
A0A368FDJ1 484-661 None
A0A077ZJH8 356-530 None
A0A0E0F153 814-972 None
A0A452YQH6 7-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.