DPCstruct | MC50889

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)107 ± 19 aa
Standard deviation of domain lengths18.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score89.25
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.79
Pfam Score100.00
Assigned Pfam label(s) PF19291

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V3Y0U5 7-122 PHVLREYALLADGERGIVIGPRGDCCWMCLPRWDSPAVFGSLLGGNGVYAVSPDHPRFVWGGRYELGSLIWRSRWVTTDGIVECREA…
C7M368 253-373 ALPLEQYGFVGDLHTGAMIGAEGSVAWLCVPRFDADACFASLLGDESNGTFRIAPSGPFESTQTYVEDTLVLETTFATRTGRAKVID…
A0A2A2K6Z5 398-539 None
A0A251XRH8 17-105 None
A0A3M1D9K9 1-104 None
A0A511D036 5-89 None
A0A2P6NRF1 423-533 None
A0A286I4T9 3-83 None
A0A7W5HES6 1-122 None
A0A5C3M0F5 214-324 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.