DPCstruct | MC50806

Metacluster Properties and Pfam Annotations

Number of structural domains389
Mean domain length (aa)118 ± 20 aa
Standard deviation of domain lengths19.75
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.70
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)19.79
Pfam Score99.40
Assigned Pfam label(s) PF02508- PF04205

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J4VXD4 16-117 PMYTASAEEAAYRVVEVEEMGKHGPIRLAVTIYDSSYVRHVEVLDMREVKGNGIKKREFLDQFNGKSANDPLRIGRDIDAVTGATIS…
A0A7X7WYG1 33-161 EIVKKTYPSATKIVKINDIWNKAVDKRGKVLGYVFNSSEYGKDIRGFRGPVPILIVTDKNQKIRKVTAFNNNETPKYLSKVAAEGLF…
H3NK29 186-339 None
A0A848VCP7 44-174 None
A0A3C0BK89 217-348 None
A0A7X6DSQ7 355-485 None
A0A7K0P042 146-262 None
A0A354VJ35 76-183 None
M1Z269 2-77 None
Q3Z9P1 42-177 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.