DPCstruct | MC50789

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)401 ± 70 aa
Standard deviation of domain lengths70.18
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.51
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)15.61
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A838VH46 32-394 FTSVWGCLHGVTPDNSSRQSLARVRESIDRHIWVARRGLGQIGNGAINFHSLLNCQLNKFKANVSMLQNAGMSIEHDRVHISETALN…
A0A397IG23 530-978 SDPIEKSQDFGNVDEAWKDVDLVAYTSTLKIGVSCTNPKFERAFCFFKSYIETNAGTNQMLFRMRCIKEYTCHIEQRSSNLPITEEG…
B8IMA6 4-415 None
K9V5K9 568-994 None
A0A7U0HXB7 27-385 None
A0A7X6CAR2 416-943 None
A0A397JRJ2 208-628 None
A0A7U9KE43 526-952 None
A0A7W8K9M7 12-336 None
A0A2D6PNU1 707-1130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.