DPCstruct | MC5076

Metacluster Properties and Pfam Annotations

Number of structural domains82
Mean domain length (aa)423 ± 87 aa
Standard deviation of domain lengths86.98
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.89
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.46
Pfam Score96.43
Assigned Pfam label(s) PF19278- PF02538- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A448UPH6 34-521 LEFKERDPIGYEKMFSKLRGGIVHARETAKRIAASPIVEQEGELCFTLYNAVGDSVLTSTGIIIHVGTMGSAIKYMVENNWEDNPGI…
V9VXD6 8-438 LSPARLQVMWNRLLAVVEEQGQTLIRAAFSPIVRECGDISAGIFDAEGRMLAQAVTGTPGHINTMAEAVLHLRERFPVETMKPGDIF…
A0A537TZL6 13-414 None
E7F6Z6 740-1266 None
A0A7C1BLX2 4-430 None
A0A7W0N1A0 1-277 None
A0A538A926 1-381 None
B8IKP0 12-445 None
A0A849WU36 8-392 None
A0A7X3RVC0 9-478 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.