DPCstruct | MC50758

Metacluster Properties and Pfam Annotations

Number of structural domains426
Mean domain length (aa)282 ± 66 aa
Standard deviation of domain lengths66.23
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score87.45
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.76
Pfam Score96.97
Assigned Pfam label(s) CL0323- CL0322- CL0431- PF02620- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6B1MTX2 2-129 RGRLMQALPSGGVMVSVQAAEADVLPLLAGREAQVSLAAVNGPHSTVISGAETTVMEIAGQFEAHGVKTKRLRVSHAFHSPLMEPML…
A0A246RJ50 24-320 SRLRRWLTAPATAPPAGTDDSVVAGICVHLIQLCDLQPRRAALDTVTAAIGHSIGLQAAIVAGLRPKRPDAFLALAETSLRLVALSL…
I1CLV2 33-353 None
H6SS55 30-341 None
A0A2V1DDT1 112-447 None
A0A2V1D3K2 13-296 None
A0A0G4HAB8 315-645 None
A0A1L9VMG8 338-612 None
A0A067BW59 90-409 None
A0A2N9IPA8 883-1158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.