DPCstruct | MC50638

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)97 ± 13 aa
Standard deviation of domain lengths13.22
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.74
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)62.87
Pfam Score98.00
Assigned Pfam label(s) PF00177- PF00223

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067JLK3 17-117 IFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWFFLCAHFVWAFSLMFLFSGRGYWQELIESIVWVHNKLTVAPATQPKALSIIQGR…
A0A0R8RYU6 97-201 NFAQSANTINGWLRDFLWAQSSQVIQSYGSALSAYGLIFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSI…
A0A2G2XC02 293-383 None
A0A6S7PQ45 175-286 None
A0A7J9LF24 72-176 None
U5D1H4 22-134 None
A0A3B6PKD4 550-658 None
A0A368PEM4 151-258 None
A0A5D2K9K1 35-127 None
A0A2G3B988 140-236 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.