DPCstruct | MC506

Metacluster Properties and Pfam Annotations

Number of structural domains122
Mean domain length (aa)148 ± 23 aa
Standard deviation of domain lengths22.55
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score66.81
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)43.10
Pfam Score100.00
Assigned Pfam label(s) PF00010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D6LRR5 2-131 KILESKIHSLETFLRSRRNKRRGHAVPLTLTLKEDYVHIRAKRGQATNSQSLAERLGRKKISERMKLLQDLVPECSKIIGKAIMLDE…
A0A453M4N0 11-169 PASEDDSASARPVSTSGGGGQDLTDAEAKRFKANKSSDENGSFRKDAEADSRNASKAVDQNPPPPKQDFIHVRARRGQATDSHSLAE…
A0A2K1ITE9 27-156 None
A0A2K1J068 308-461 None
A0A2G3APS4 2-149 None
A0A1P8B161 107-263 None
A0A4Y1QQN2 2-152 None
A0A4S8IGM5 51-218 None
A2Z2Z7 5-139 None
A0A7N0UM46 13-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.